Regression of mesenchymal hamartoma of the liver with sarcoma chemotherapy.

Abstract

We present a young patient with metastatic Ewing sarcoma that had hepatic lesions. As we were unaware of hepatic metastases in Ewing sarcoma, liver biopsy was performed. The pathologic findings were diagnostic of mesenchymal hamartoma of the liver. Surprisingly, the combined chemotherapy for metastatic sarcoma resulted in almost complete resolution of the hamartoma in the liver. This option may be useful in extreme cases when resection is not feasible.

• Authors: Amir A Kuperman, Liora Kornreich, Meora Feinmesser, Shifra Ash, Issac Yaniv, Ian J Cohen
• Journal: Journal of pediatric hematology/oncology (J Pediatr Hematol Oncol) Vol. 35 Issue 1 Pg. e25-6 (Jan 2013) ISSN: 1536-3678 [Electronic] United States
• PMID: 22935658 (Publication Type: Case Reports, Journal Article)

Chemical References

• Dactinomycin
• Vincristine
• Etoposide
• Doxorubicin
• Cyclophosphamide
• Ifosfamide

Topics

• Adult
• Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
• Bone Neoplasms (diagnosis)
• Cyclophosphamide (administration & dosage)
• Dactinomycin (administration & dosage)
• Diagnostic Errors
• Doxorubicin (administration & dosage)
• Etoposide (administration & dosage)
• Female
• Hamartoma (drug therapy, pathology)
• Humans
• Ifosfamide (administration & dosage)
• Liver Neoplasms (drug therapy, secondary)
• Mesoderm (pathology)
• Prognosis
• Sarcoma, Ewing (diagnosis)
• Vincristine (administration & dosage)
• Young Adult