Abstract |
We describe two patients with otologic infections caused by Mycobacterium massiliense (M. abscessus subsp. bolletti) which were identified using erm(41) PCR, 23S rRNA, and rpoB gene sequence analysis. They were middle-aged adults with underlying otologic diseases and were treated successfully with clarithromycin-based combination regimens for 3 and 9 months, respectively.
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Authors | Meng-Rui Lee, Hsih-Yeh Tsai, Aristine Cheng, Chia-Ying Liu, Yu-Tsung Huang, Chun-Hsing Liao, Sheng-Kai Liang, Li-Na Lee, Po-Ren Hsueh |
Journal | Journal of clinical microbiology
(J Clin Microbiol)
Vol. 50
Issue 11
Pg. 3754-6
(Nov 2012)
ISSN: 1098-660X [Electronic] United States |
PMID | 22933592
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Anti-Bacterial Agents
- DNA, Bacterial
- DNA, Ribosomal
- RNA, Ribosomal, 23S
- Methyltransferases
- DNA-Directed RNA Polymerases
- RNA polymerase beta subunit
- Clarithromycin
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Topics |
- Anti-Bacterial Agents
(administration & dosage)
- Clarithromycin
(administration & dosage)
- DNA, Bacterial
(chemistry, genetics)
- DNA, Ribosomal
(chemistry, genetics)
- DNA-Directed RNA Polymerases
(genetics)
- Drug Therapy, Combination
(methods)
- Humans
- Male
- Mastoiditis
(drug therapy, microbiology)
- Methyltransferases
(genetics)
- Microbial Sensitivity Tests
- Middle Aged
- Mycobacterium
(classification, drug effects, genetics, isolation & purification)
- Mycobacterium Infections
(diagnosis, drug therapy, microbiology)
- Otitis Media
(drug therapy, microbiology)
- RNA, Ribosomal, 23S
(genetics)
- Sequence Analysis, DNA
- Treatment Outcome
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