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Filaggrin degradation by caspase-14 is required for UVB photoprotection but does not influence allergic sensitization in a mouse model of atopic dermatitis.

AuthorsMichael Devos, Janne Prawitt, Delphine Staumont-Salle, Esther Hoste, Sebastién Fleury, Emmanuel Bouchaert, Barbara Gilbert, Saskia Lippens, Peter Vandenabeele, David Dombrowicz, Wim Declercq
JournalThe Journal of investigative dermatology (J Invest Dermatol) Vol. 132 Issue 12 Pg. 2857-60 (Dec 2012) ISSN: 1523-1747 [Electronic] United States
PMID22931922 (Publication Type: Letter, Research Support, Non-U.S. Gov't)
Chemical References
  • Filaggrin Proteins
  • Intermediate Filament Proteins
  • Casp14 protein, mouse
  • Caspases
Topics
  • Animals
  • Caspases (metabolism)
  • Dermatitis, Atopic (immunology, metabolism, pathology)
  • Disease Models, Animal
  • Filaggrin Proteins
  • Hypersensitivity (immunology, metabolism)
  • Intermediate Filament Proteins (metabolism)
  • Mice
  • Skin (immunology, metabolism, radiation effects)
  • Ultraviolet Rays (adverse effects)

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