Abstract | OBJECTIVE: This study was carried out to evaluate the effects of a single pre-operative sub-mucosal injection of dexamethasone after third molar surgery to see the effects on post-operative discomfort. METHODS: This study was a prospective, double-blind, randomized, clinical trial. The subjects were forty patients who underwent surgical removal of the mandibular impacted third molar under local anesthesia and after being randomly assigned to receive either an 8 mg dexamethasone as submucosal injection or a normal saline injection into the lower buccal vestibule adjacent to the third molar. The maximum interincisal distance and facial contours were measured at the baseline and post-surgically on Day 2 and 7. Post-operative pain was evaluated subjectively using a visual analog scale and objectively by counting the number of analgesic tablets used. All subjects were operated upon by the same investigator to minimize the difference from inter-operator variability. RESULTS: There was a significant difference in the measurements of the degree of swelling and trismus between the two groups on the 2nd post-operative day. In contrast, there was no statistically significant difference between the groups on the 7th post-operative day. The test group also used fewer analgesics post-operatively. CONCLUSIONS:
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Authors | S P Deo |
Journal | JNMA; journal of the Nepal Medical Association
(JNMA J Nepal Med Assoc)
2011 Apr-Jun
Vol. 51
Issue 182
Pg. 72-8
ISSN: 0028-2715 [Print] Nepal |
PMID | 22916516
(Publication Type: Journal Article, Randomized Controlled Trial)
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Chemical References |
- Anti-Inflammatory Agents
- Glucocorticoids
- Dexamethasone
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Topics |
- Adult
- Anti-Inflammatory Agents
(administration & dosage)
- Dexamethasone
(administration & dosage)
- Edema
(prevention & control)
- Female
- Glucocorticoids
(administration & dosage)
- Humans
- Male
- Molar, Third
(surgery)
- Pain Measurement
- Pain, Postoperative
(prevention & control)
- Prospective Studies
- Young Adult
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