Design, properties, and effective use of the oral chelator L1 and other alpha-ketohydroxypyridines in the treatment of transfusional iron overload in thalassemia.

• Authors: G J Kontoghiorghes
• Journal: Annals of the New York Academy of Sciences (Ann N Y Acad Sci) Vol. 612 Pg. 339-50 ( 1990) ISSN: 0077-8923 [Print] United States
• PMID: 2291562 (Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't, Review)

Chemical References

• Chelating Agents
• Iron Chelating Agents
• Pyridines
• Pyridones
• Deferiprone
• Iron

Topics

• Chelating Agents (chemical synthesis, chemistry, therapeutic use)
• Deferiprone
• Drug Design
• Humans
• Iron (blood)
• Iron Chelating Agents
• Pyridines (chemical synthesis, chemistry, therapeutic use)
• Pyridones (therapeutic use)
• Thalassemia (therapy)
• Transfusion Reaction