[Lipoproteins as coronary risk or non-risk indicators in elderly people].

Abstract

Lipid and apolipoprotein (apo) levels were investigated in 98 (68 female, 30 male) subjects older than 85 years and 86 (59 female, 27 male) subjects aged 65-75 years. The mean cholesterol level of the long-lived persons who were free from overt degenerative arterial disease was 5.2 mmol/l and ranged markedly below the mean level of the population. Comparing both age groups, the triglyceride level of the high-age subjects was at 0.3 mmol/l, significantly lower; HDL-cholesterol and apo A-I at 0.15 mmol/l or 0.3 g/l were higher. Cholesterol, LDL-cholesterol, and apo B only tended to be lower in the higher age. Subjects suffering from degenerative arterial disease (circulatory disturbance, hypertonia, diabetes mellitus), especially the long-lived group, had a more marked unfavorable lipoprotein profile. Subjects over 85 years (13%) had markedly less disturbance in lipoprotein metabolism of high atherogenic potency (hyper-beta-, hypo-alpha-lipoproteinemia) than did subjects 65-75 years old (23%). Hypertriglyceridemia is with 38% or rather 21% very frequent and seems to be of less atherogenic potency. Hyper-alpha-lipoproteinemia as anti-risk factor for coronary heart diseases was established more frequently in the long-lived group with 13% in comparison to 3.5% in those 65-75 years of age.

• Authors: W Herrmann, S Hanf, H G Lindhofer
• Journal: Zeitschrift fur Gerontologie (Z Gerontol) 1990 Nov-Dec Vol. 23 Issue 6 Pg. 338-44 ISSN: 0044-281X [Print] Germany
• Vernacular Title: Lipoproteine als koronare Risiko- oder Antirisikoindikatoren bei alten Menschen.
• PMID: 2291302 (Publication Type: English Abstract, Journal Article)

Chemical References

• Apolipoproteins
• Lipoproteins
• Triglycerides
• Cholesterol

Topics

• Aged
• Aged, 80 and over
• Aging (blood)
• Apolipoproteins (blood)
• Cholesterol (blood)
• Coronary Disease (etiology)
• Female
• Humans
• Lipoproteins (blood)
• Male
• Risk Factors
• Triglycerides (blood)