Mesial side ovarian incision for laparoscopic dermoid cystectomy: a safe and ovarian tissue-preserving technique.

Abstract

OBJECTIVE:

To evaluate safety and efficacy, in terms of spillage risk and ovarian tissue preservation, of mesial incision for laparoscopic dermoid cystectomy.

DESIGN:

Randomized controlled trial.

SETTING:

University.

PATIENT(S):

Sixty-seven women with dermoid cysts.

INTERVENTION(S):

Laparoscopic dermoid cystectomy performed by mesial incision (33 patients, study group) or antimesial incision (34 patients, control group).

MAIN OUTCOME MEASURE(S):

Spillage of intracystic content rate, operative times, chemical peritonitis rate, and intraoperative blood loss (ΔHb) as primary outcomes. Postoperative ovarian reserve (ΔFSH levels, basal antral follicle number, mean ovarian diameter, and peak systolic velocity at 3 and 12 months after surgery) as secondary outcome.

RESULT(S):

Spillage of intracystic content rate and operative time were significantly lower in the study than in the control group. None developed chemical peritonitis. ΔHb was higher in the study group but not significantly. During the follow-up, median FSH values were significantly lower in the study group, with no differences in the E(2) levels. Moreover, median basal antral follicle number, median ovarian diameter, and median peak systolic velocity were significantly higher in the study group.

CONCLUSION(S):

Ovarian mesial-side incision appears to be a safe as well as tissue-sparing technique.

CLINICAL TRIAL REGISTRATION NUMBER:

• Authors: Michele Morelli, Rita Mocciaro, Roberta Venturella, Alberto Imperatore, Daniela Lico, Fulvio Zullo
• Journal: Fertility and sterility (Fertil Steril) Vol. 98 Issue 5 Pg. 1336-40.e1 (Nov 2012) ISSN: 1556-5653 [Electronic] United States
• PMID: 22884658 (Publication Type: Journal Article, Randomized Controlled Trial, Video-Audio Media)
• Copyright: Copyright © 2012 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

Chemical References

• Biomarkers
• Follicle Stimulating Hormone, Human

Topics

• Biomarkers (blood)
• Blood Loss, Surgical
• Chi-Square Distribution
• Female
• Fertility Preservation (adverse effects)
• Follicle Stimulating Hormone, Human (blood)
• Gynecologic Surgical Procedures (adverse effects, methods)
• Humans
• Laparoscopy (adverse effects)
• Organ Sparing Treatments (adverse effects)
• Ovarian Follicle (diagnostic imaging, metabolism)
• Ovarian Neoplasms (surgery)
• Ovary (diagnostic imaging, metabolism, physiopathology, surgery)
• Peritonitis (etiology)
• Risk Assessment
• Risk Factors
• Teratoma (surgery)
• Time Factors
• Treatment Outcome
• Ultrasonography