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Introduction of β-carotene-rich orange sweet potato in rural Uganda resulted in increased vitamin A intakes among children and women and improved vitamin A status among children.

Abstract
Vitamin A deficiency (VAD) persists in Uganda and the consumption of β-carotene-rich orange sweet potato (OSP) may help to alleviate it. Two large-scale, 2-y intervention programs were implemented among Ugandan farmer households to promote the production and consumption of OSP. The programs differed in their inputs during year 2, with one being more intensive (IP) and the other being reduced (RP). A randomized, controlled effectiveness study compared the impact of the IP and RP with a control on OSP and vitamin A intakes among children aged 6-35 mo (n = 265) and 3-5 y (n = 578), and women (n = 573), and IP compared with control on vitamin A status of 3- to 5-y-old children (n = 891) and women (n = 939) with serum retinol <1.05 μmol/L at baseline. The net OSP intake increased in both the IP and RP groups (P < 0.01), accounting for 44-60% of vitamin A intake at follow-up. The prevalence of inadequate vitamin A intake was reduced in the IP and RP groups compared with controls among children 6-35 mo of age (>30 percentage points) and women (>25 percentage points) (P < 0.01), with no differences between the IP and RP groups of children (P = 0.75) or women (P = 0.17). There was a 9.5 percentage point reduction in prevalence of serum retinol <1.05 μmol/L for children with complete data on confounding factors (n = 396; P < 0.05). At follow-up, vitamin A intake from OSP was positively associated with vitamin A status (P < 0.05). Introduction of OSP to Ugandan farming households increased vitamin A intakes among children and women and was associated with improved vitamin A status among children.
AuthorsChristine Hotz, Cornelia Loechl, Abdelrahman Lubowa, James K Tumwine, Grace Ndeezi, Agnes Nandutu Masawi, Rhona Baingana, Alicia Carriquiry, Alan de Brauw, Jonnalagadda V Meenakshi, Daniel O Gilligan
JournalThe Journal of nutrition (J Nutr) Vol. 142 Issue 10 Pg. 1871-80 (Oct 2012) ISSN: 1541-6100 [Electronic] United States
PMID22875553 (Publication Type: Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.)
Chemical References
  • beta Carotene
  • Vitamin A
Topics
  • Adult
  • Anthropometry
  • Child, Preschool
  • Cross-Sectional Studies
  • Family Characteristics
  • Female
  • Follow-Up Studies
  • Humans
  • Infant
  • Ipomoea batatas (chemistry)
  • Male
  • Nutrition Assessment
  • Nutritional Status
  • Regression Analysis
  • Rural Population
  • Uganda (epidemiology)
  • Vitamin A (administration & dosage, blood)
  • Vitamin A Deficiency (blood, drug therapy, epidemiology)
  • beta Carotene (administration & dosage)

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