Abstract |
Churg-Strauss syndrome (CSS) is a rare autoimmune vasculitis of unknown etiology that involves small- and medium-sized blood vessels. Its onset is thought to be associated with adult-onset asthma, and vasculitis typically involves vessels in the lungs. However, due to increased blood and tissue eosinophilia, vasculitis may result in the involvement multiple systems of (neurological, skin, etc.). We report a case of CSS with manifestations that included skin purpura and severe peripheral nerve degeneration in a 56-year-old woman with a recent history of asthma. After the treatment with methylprednisolone and standard immunosuppressive therapy, her rashes resolved, there were no acute asthma attacks, and the numbness in her lower limbs improved.
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Authors | Jing Yan Xiang, Yu Wu Zhao, Jian Liang Fu, Xiao Juan Cheng, Qin Xue, Yin Wang |
Journal | Medicina (Kaunas, Lithuania)
(Medicina (Kaunas))
Vol. 48
Issue 5
Pg. 244-8
( 2012)
ISSN: 1648-9144 [Electronic] Switzerland |
PMID | 22864271
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Anti-Inflammatory Agents
- Methylprednisolone
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Topics |
- Anti-Inflammatory Agents
(therapeutic use)
- Asthma
(complications)
- Churg-Strauss Syndrome
(complications, drug therapy, pathology)
- Female
- Humans
- Immunosuppression Therapy
- Methylprednisolone
(therapeutic use)
- Middle Aged
- Nerve Degeneration
(drug therapy, etiology, pathology)
- Purpura
(drug therapy, etiology, pathology)
- Treatment Outcome
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