Abstract | OBJECTIVE: METHOD: Normal mice were taken as the control group, and hyperlipemia mice were divided into the model group, Lycium ruthenicum anthocyanins low, medium and high dose groups, and the simvastatin drug control group. After the oral administration, blood lipid indicators were detected by enzymatic analysis. The histomorphological changes in aortas, hearts and livers were observed, and liver-related indicators were determined by using hematoxylin- eosin (HE) staining. RESULT: CONCLUSION: L. ruthenicum anthocyanins can interfere the formation of AS, while lowering blood lipid levels in mice.
|
Authors | Li Lin, Jin Li, Haiying Lv, Yuting Ma, Yiping Qian |
Journal | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
(Zhongguo Zhong Yao Za Zhi)
Vol. 37
Issue 10
Pg. 1460-6
(May 2012)
ISSN: 1001-5302 [Print] China |
PMID | 22860462
(Publication Type: English Abstract, Journal Article, Research Support, Non-U.S. Gov't)
|
Chemical References |
- Anthocyanins
- Lipids
- Glutathione Peroxidase
|
Topics |
- Animals
- Anthocyanins
(therapeutic use)
- Atherosclerosis
(prevention & control)
- Body Weight
(drug effects)
- Glutathione Peroxidase
(metabolism)
- Hypercholesterolemia
(blood, drug therapy, pathology)
- Lipids
(blood)
- Liver
(pathology)
- Lycium
(chemistry)
- Male
- Mice
- Phytotherapy
|