Abstract | BACKGROUND: OBJECTIVE: The objective of this study was to present data on 24 of 591 dermatitis patients with reactions to SSO and/or sorbitan monooleate (SMO) on patch testing. METHODS: A retrospective chart review was conducted on 591 consecutive dermatitis patients patch tested from November 2008 to May 2010. In addition to being tested to a modified North American Contact Dermatitis Group standard series, all patients were tested to a cosmetic series. RESULTS: Of the 591 patients tested, 24 reacted to SSO and/or SMO (4.1%), 19 (3.2%) reacted to SSO alone, 1 (0.17%) to SMO alone, and 4 (0.68%) reacted to both. Of the 24 sorbitan-allergic patients, 2 (8.3%) reacted to any of 4 corticosteroid screening chemicals tested. CONCLUSIONS: In this follow-up study, 4.1% of 591 dermatitis patients reacted to SSO and/or SMO. Given the presence of SSO in many popular topical corticosteroid formulations, clinicians should consider allergy to sorbitans when patients do not improve with topical corticosteroid therapy.
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Authors | Brienne D Cressey, Neal Kumar, Pamela L Scheinman |
Journal | Dermatitis : contact, atopic, occupational, drug
(Dermatitis)
2012 Jul-Aug
Vol. 23
Issue 4
Pg. 158-61
ISSN: 2162-5220 [Electronic] United States |
PMID | 22828254
(Publication Type: Journal Article)
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Chemical References |
- Cosmetics
- Glucocorticoids
- Hexoses
- Surface-Active Agents
- sorbitan monooleate
- sorbitan sesquioleate
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Topics |
- Adolescent
- Adult
- Child
- Cosmetics
(adverse effects)
- Dermatitis, Allergic Contact
(etiology, immunology)
- Female
- Follow-Up Studies
- Glucocorticoids
(adverse effects, immunology)
- Hexoses
(adverse effects, immunology)
- Humans
- Male
- Patch Tests
(methods)
- Surface-Active Agents
(adverse effects)
- Young Adult
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