Vasospastic angina with J-wave pattern and polymorphic ventricular tachycardia effectively treated with quinidine.

Abstract

BACKGROUND:

Myocardial ischemia during coronary spasm may generate malignant ventricular arrhythmias. The J-wave pattern was suggested to be a marker of a disorder associated with life-threatening arrhythmias.

RESULTS:

We report the case of a patient with vasospastic angina and J-wave pattern in inferior and lateral leads associated with polymorphic ventricular tachycardia which was effectively treated only with quinidine-vasodilating drugs were not able to prevent the arrhythmia although they were effective in preventing ischemic events.

CONCLUSION:

The J-wave pattern in inferolateral leads may be a sign of electrical vulnerability to lethal ventricular arrhythmia in patients suffering from vasospastic angina--quinidine can effectively prevent such arrhythmias in these patients.

• Authors: Jerzy Sacha, Szymon Barabach, Piotr Feusette, Piotr Kukla
• Journal: Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc (Ann Noninvasive Electrocardiol) Vol. 17 Issue 3 Pg. 286-90 (Jul 2012) ISSN: 1542-474X [Electronic] United States
• PMID: 22816550 (Publication Type: Case Reports, Journal Article)
• Copyright: ©2012, Wiley Periodicals, Inc.

Chemical References

• Verapamil
• Molsidomine
• Quinidine
• Isosorbide

Topics

• Angina Pectoris, Variant (complications, diagnosis, therapy)
• Atrial Fibrillation (diagnosis, etiology, surgery)
• Atrial Flutter (diagnosis, etiology, surgery)
• Catheter Ablation (methods)
• Combined Modality Therapy
• Defibrillators, Implantable
• Drug Therapy, Combination
• Electrocardiography (methods)
• Electrocardiography, Ambulatory (methods)
• Exercise Test (methods)
• Follow-Up Studies
• Humans
• Isosorbide (therapeutic use)
• Male
• Middle Aged
• Molsidomine (therapeutic use)
• Quinidine (therapeutic use)
• Risk Assessment
• Severity of Illness Index
• Tachycardia, Ventricular (complications, diagnosis, therapy)
• Treatment Outcome
• Verapamil (therapeutic use)