[Experience with the use of IRS-19 for the rehabilitation of children after acute respiratory infections].

Abstract

The purpose of this work was to evaluate the efficacy of the prevention of recurrent respiratory infections with the use of the immunomodulatory respiratory spray (IRS-19). The study involved 60 children at the age from 4 to 7 years allocated to three groups. Group 1 was comprised of 20 children treated by two daily irrigation of nasal sinuses with a seawater solution. Group 2 included 20 children treated by irrigation of nasal sinuses with IRS-19 twice daily during 2 weeks.. Group 3 consisted of 20 children treated by irrigation of nasal sinuses with a saline solution and topical immunostimulator IRS-19 twice daily. It was shown that therapy with IRS-19 resulted in a more than two-fold reduction in the frequency of relapses of the acute respiratory infections as compared with control.

• Authors: L V Mukhomedzianova, I V Andriianova, I A Kashirtseva
• Journal: Vestnik otorinolaringologii (Vestn Otorinolaringol) Issue 2 Pg. 61-2 ( 2012) ISSN: 0042-4668 [Print] Russia (Federation)
• PMID: 22810641 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Adjuvants, Immunologic
• IRS 19
• Sodium Chloride

Topics

• Acute Disease
• Adjuvants, Immunologic (therapeutic use)
• Administration, Intranasal
• Bacteria (immunology)
• Child
• Child, Preschool
• Female
• Humans
• Immunomodulation (drug effects)
• Male
• Respiratory Tract Infections (drug therapy, immunology)
• Seawater
• Sodium Chloride (administration & dosage)