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Complications of plasma exchange in patients with neurological diseases.

AbstractPlasma exchange has proven to be effective in diseases of established or presumed autoimmune etiology as well as in hyperviscosity syndromes and some rare metabolic disorders. Its application is thought to be relatively safe; nevertheless, severe complications may occur. We therefore analyzed the complications of 291 exchanges in 39 patients with neurological diseases. Minor complications developed in 4.8% and major complications in 2.7% of procedures, including one death. Severe infections and technical problems have been the most serious side effects, sometimes followed by organ failure or even death.
AuthorsT Henze, H W Prange, J Talartschik, K W Rumpf (Affiliation: Abteilung für Neurologie, Georg-August-Universität, Göttingen.)
JournalKlinische Wochenschrift (Klin Wochenschr) Vol. 68 Issue 23 Pg. 1183-8 (Dec 4 1990) ISSN: 0023-2173 GERMANY
PMID2280582 (Publication Type: Case Reports, Comparative Study, Journal Article)
Topics
  • Adult
  • Aged
  • Aged, 80 and over
  • Female
  • Humans
  • Male
  • Middle Aged
  • Multiple Sclerosis (complications)
  • Myasthenia Gravis (complications)
  • Nervous System Diseases (complications)
  • Plasma Exchange (adverse effects)
  • Polyradiculoneuropathy (complications)