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Peroxisome proliferator-activated receptors of trophoblast cells in miscarriage.

Abstract
Comparative histological study of uterine curettage specimens in missed abortion in women with spontaneous and induced pregnancy and progressing spontaneous pregnancy revealed similar changes in the endometrium and placental villi. Immunohistochemical assay showed enhanced expression of PPARĪ³ and increased proliferation index (Ki-67) in cells of the villous and extravillous trophoblasts in missed abortion.
AuthorsN V Alexandrova, E A Dubova, O R Baev, A I Shchegolev, G T Sukhikh
JournalBulletin of experimental biology and medicine (Bull Exp Biol Med) Vol. 152 Issue 6 Pg. 768-71 (Apr 2012) ISSN: 1573-8221 [Electronic] United States
PMID22803185 (Publication Type: Journal Article)
Chemical References
  • Ki-67 Antigen
  • PPAR gamma
Topics
  • Abortion, Spontaneous (genetics, metabolism, pathology)
  • Adult
  • Cell Proliferation
  • Chorionic Villi (metabolism, pathology)
  • Endometrium (pathology)
  • Female
  • Fertilization in Vitro
  • Gene Expression
  • Humans
  • Immunohistochemistry
  • Ki-67 Antigen (genetics, metabolism)
  • PPAR gamma (genetics, metabolism)
  • Pregnancy
  • Pregnancy Trimester, First (genetics, metabolism)
  • Trophoblasts (metabolism, pathology)

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