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Activities of daily living in progressive non-fluent aphasia, logopenic progressive aphasia and Alzheimer's disease.

AbstractBACKGROUND/AIMS:
This study examined functional changes in progressive non-fluent aphasia (PNFA) and logopenic progressive aphasia (LPA) and Alzheimer's disease (AD) and the association between function, cognition and behaviour.
METHODS:
59 patients were assessed with the Disability Assessment of Dementia (DAD), Addenbrooke's Cognitive Examination Revised (ACE-R) and the Cambridge Behavioural Inventory Revised (CBI-R).
RESULTS:
No differences between groups in basic and instrumental activities of daily living (ADLs), and total ACE-R scores were found; there were correlations between total DAD and ACE-R scores for PNFA and LPA. Over 12 months, PNFA showed the marked decline of basic ADLs, whereas all three groups showed marked decline of instrumental ADLs.
CONCLUSION:
PNFA, LPA and AD appear functionally similar when matched for disease duration. The rate of decline of ADLs depends, however, on disease diagnosis.
AuthorsJ Jang, N Cushing, L Clemson, J R Hodges, E Mioshi
JournalDementia and geriatric cognitive disorders (Dement Geriatr Cogn Disord) Vol. 33 Issue 5 Pg. 354-60 ( 2012) ISSN: 1421-9824 [Electronic] Switzerland
PMID22796966 (Publication Type: Journal Article)
CopyrightCopyright © 2012 S. Karger AG, Basel.
Topics
  • Activities of Daily Living
  • Aged
  • Alzheimer Disease (physiopathology)
  • Anomia (etiology, physiopathology)
  • Aphasia (complications, physiopathology)
  • Disease Progression
  • Female
  • Humans
  • Male
  • Middle Aged
  • Neuropsychological Tests
  • Primary Progressive Nonfluent Aphasia (physiopathology)

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