HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Totally laparoscopic stapled distal pancreatectomy.

AbstractPURPOSE:
To evaluate the outcomes of totally laparoscopic distal pancreatectomy (LDP).
METHODS:
A prospective database of patients treated within a single institution was studied retrospectively. Between March 2003 and January 2010, 15 patients underwent pancreatic transection with the use of a stapler, followed by sealing of the pancreatic stump with fibrin-coated collagen fleece (TachoComb) in LDP.
RESULTS:
LDP was completed successfully in all 15 patients. The median operating time and blood loss were 168 min (range 105-213 min) and 36 ml (range 12-89 ml), respectively. The median drain amylase level peaked at 969 IU/l (93-3077 IU/l) on postoperative day (POD) 1, and then dropped to 165 IU/l (30-846 IU/l) on POD 3. The median hospital stay was 7 days (range 4-15 days). Biochemical pancreatic leaks developed in three patients (20 %), but there was no clinical pancreatic fistula or postoperative hemorrhage.
CONCLUSIONS:
Our study shows that the combined use of a stapler and TachoComb decreased the incidence of pancreatic fistulas after LDP. This procedure offers more efficient and consistent results than those achieved by closing the pancreatic stump by stapling alone.
AuthorsHirokatsu Katagiri, Akira Sasaki, Hiroyuki Nitta, Takeshi Takahara, Satoshi Nishizuka, Go Wakabayashi
JournalSurgery today (Surg Today) Vol. 42 Issue 10 Pg. 940-4 (Oct 2012) ISSN: 1436-2813 [Electronic] Japan
PMID22790708 (Publication Type: Evaluation Study, Journal Article)
Chemical References
  • Drug Combinations
  • Tissue Adhesives
  • tachocomb
  • Fibrinogen
  • Aprotinin
  • Thrombin
Topics
  • Adult
  • Aged
  • Aprotinin (administration & dosage)
  • Drug Combinations
  • Female
  • Fibrinogen (administration & dosage)
  • Humans
  • Laparoscopy
  • Male
  • Middle Aged
  • Pancreatectomy (instrumentation, methods)
  • Pancreatic Diseases (surgery)
  • Pancreatic Fistula (etiology, prevention & control)
  • Postoperative Complications (prevention & control)
  • Retrospective Studies
  • Surgical Staplers
  • Surgical Stapling (instrumentation, methods)
  • Thrombin (administration & dosage)
  • Tissue Adhesives (administration & dosage)
  • Treatment Outcome

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: