Imaging of endolymphatic and perilymphatic fluid after intravenous administration of single-dose gadodiamide.

Abstract

To visualize endolymph as bright signal after intravenous injection of single-dose gadodiamide, we shortened the inversion time of heavily T(2)-weighted 3-dimensional (3D) fluid-attenuated inversion recovery (FLAIR) to 2050 ms. In 14 patients with suspected Ménière's disease, we observed high signal of vestibular endolymph in all ears, including 6 ears without vestibular endolymphatic hydrops. We observed high signal of cochlear endolymph in 17 ears with cochlear endolymphatic hydrops but not 11 ears without cochlear endolymphatic hydrops.

• Authors: Shinji Naganawa, Masahiro Yamazaki, Hisashi Kawai, Kiminori Bokura, Michihiko Sone, Tsutomu Nakashima
• Journal: Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine (Magn Reson Med Sci) Vol. 11 Issue 2 Pg. 145-50 ( 2012) ISSN: 1880-2206 [Electronic] Japan
• PMID: 22790302 (Publication Type: Journal Article)

Chemical References

• Contrast Media
• gadodiamide
• Gadolinium DTPA

Topics

• Adolescent
• Adult
• Aged
• Contrast Media (administration & dosage)
• Endolymph (cytology)
• Gadolinium DTPA (administration & dosage)
• Humans
• Injections, Intravenous
• Male
• Meniere Disease (pathology)
• Middle Aged
• Perilymph (cytology)
• Reproducibility of Results
• Sensitivity and Specificity
• Young Adult