Dietary effects of pure and diacylglycerol-rich rice bran oil on growth pattern and lipid profile of rats.

Abstract

Diacylglycerol (DAG) oil is becoming quite well known for its beneficial effects on obesity and weight related disorders as they are digested and metabolized in a different way, which significantly reduces body weight. The present study was conducted to evaluate the nutritional effect of rice bran oil (RBO) and DAG-rich rice bran oil on rat model. DAG-rich RBO (46.10% DAG) was prepared in the laboratory by enzymatic (TLIM) glycerolysis process. For the feeding experiment, rats (average body weight 130 g) were divided into two groups, each consisting of eight rats. Group RBO was taken as control while DAG-rich RBO (Group DGR) was taken as experimental. Food efficiency ratio, lipid profile of plasma, liver, mesentery and erythrocyte membrane (EM) lipid profile, plasma leptin content, HMG-CoA reductase activity were measured using standard procedures. The results indicated that DAG-rich rice bran oil significantly decreased body weight of rats and content of total cholesterol and triglyceride in plasma compared to the control RBO. The long term use of DAG-rich rice bran oil might be useful for prevention of obesity and incidence of hypercholesterolemia.

• Authors: Rupali Dhara, Pubali Dhar, Mahua Ghosh
• Journal: Journal of oleo science (J Oleo Sci) Vol. 61 Issue 7 Pg. 369-75 ( 2012) ISSN: 1347-3352 [Electronic] Japan
• PMID: 22790167 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• 1,2-diacylglycerol
• Dietary Fats, Unsaturated
• Diglycerides
• Lipids
• Plant Oils
• Rice Bran Oil

Topics

• Animals
• Dietary Fats, Unsaturated (pharmacology)
• Diglycerides (pharmacology)
• Erythrocyte Membrane (drug effects, metabolism)
• Growth and Development (drug effects)
• Lipids (blood)
• Liver (drug effects, metabolism)
• Male
• Plant Oils (chemistry, pharmacology)
• Rats
• Rice Bran Oil