HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Evidence-based clinical recommendations regarding screening for oral squamous cell carcinomas.

AbstractBACKGROUND:
This article presents evidence-based clinical recommendations developed by a panel convened by the American Dental Association Council on Scientific Affairs. This report addresses the potential benefits and potential risks of screening for oral squamous cell carcinomas and the use of adjunctive screening aids to visualize and detect potentially malignant and malignant oral lesions.
TYPES OF STUDIES REVIEWED:
The panel members conducted a systematic search of MEDLINE, identifying 332 systematic reviews and 1,499 recent clinical studies. They selected 5 systematic reviews and 4 clinical studies to use as a basis for developing recommendations.
RESULTS:
The panel concluded that screening by means of visual and tactile examination to detect potentially malignant and malignant lesions may result in detection of oral cancers at early stages of development, but that there is insufficient evidence to determine if screening alters disease-specific mortality in asymptomatic people seeking dental care.
CLINICAL IMPLICATIONS:
The panel suggested that clinicians remain alert for signs of potentially malignant lesions or early-stage cancers while performing routine visual and tactile examinations in all patients, but particularly in those who use tobacco or who consume alcohol heavily. Additional research regarding oral cancer screening and the use of adjuncts is needed.
AuthorsMichael P Rethman, William Carpenter, Ezra E W Cohen, Joel Epstein, Caswell A Evans, Catherine M Flaitz, Frank J Graham, Philippe P Hujoel, John R Kalmar, Wayne M Koch, Paul M Lambert, Mark W Lingen, Bert W Oettmeier Jr, Lauren L Patton, David Perkins, Britt C Reid, James J Sciubba, Scott L Tomar, Alfred D Wyatt Jr, Krishna Aravamudhan, Julie Frantsve-Hawley, Jennifer L Cleveland, Daniel M Meyer, American Dental Association Council on Scientific Affairs Expert Panel on Screening for Oral Souamous Cell Carcinomas
JournalTexas dental journal (Tex Dent J) Vol. 129 Issue 5 Pg. 491-507 (May 2012) ISSN: 0040-4284 [Print] United States
PMID22779205 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S.)
Chemical References
  • Coloring Agents
  • Tolonium Chloride
Topics
  • Alcohol Drinking
  • American Dental Association
  • Asymptomatic Diseases
  • Carcinoma, Squamous Cell (diagnosis, epidemiology, mortality)
  • Coloring Agents
  • Cytodiagnosis
  • Early Detection of Cancer
  • Evidence-Based Dentistry
  • Humans
  • Incidence
  • Light
  • Mass Screening (methods)
  • Mouth Neoplasms (diagnosis, epidemiology, mortality)
  • Physical Examination
  • Practice Guidelines as Topic
  • Risk Factors
  • Smoking
  • Tolonium Chloride
  • United States (epidemiology)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: