Gastric MALT lymphoma treated with primary radiotherapy in the setting of autoimmune disease.

Abstract

Autoimmune and microbial-induced immune reactions are associated with lymphomagenesis, particularly of extranodal marginal zone B-cell lymphomas. This report presents a case of Helicobacter pylori-negative gastric extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) in the setting of Sjögren syndrome and Hashimoto thyroiditis treated with primary involved-field radiotherapy. This report describes etiologic data, diagnostic and treatment considerations, and sophisticated radiation therapy techniques aimed at reducing long-term toxicity in this indolent disease.

• Authors: Chelsea C Pinnix, Valerie Reed, Bouthaina Dabaja
• Journal: Journal of the National Comprehensive Cancer Network : JNCCN (J Natl Compr Canc Netw) Vol. 10 Issue 7 Pg. 815-9 (Jul 01 2012) ISSN: 1540-1413 [Electronic] United States
• PMID: 22773797 (Publication Type: Case Reports, Journal Article)

Topics

• Autoimmune Diseases (complications)
• Female
• Four-Dimensional Computed Tomography
• Humans
• Lymphoma, B-Cell, Marginal Zone (complications, diagnosis, radiotherapy)
• Middle Aged
• Radiotherapy, Intensity-Modulated
• Stomach Neoplasms (diagnosis, radiotherapy)