Dumping symptoms and incidence of hypoglycaemia after provocation test at 6 and 12 months after laparoscopic sleeve gastrectomy.

Abstract

BACKGROUND:

A previous study has demonstrated that symptoms suggestive of dumping syndrome appear after a provocation test early after laparoscopic sleeve gastrectomy (LSG) in 45 % of patients, and these are mainly related to early dumping. The aim of this study is to evaluate the evolution of dumping symptoms during the first postoperative year.

METHODS:

Twenty-five non-diabetic morbidly obese patients (6 male, 19 female) were evaluated with an oral glucose tolerance test (OGTT) preoperatively, at 6 weeks and at 6 months postoperatively. In addition, 12 of them repeated the OGTT at 12 months after LSG. Sigstad score was used to separate dumpers from non-dumpers and Arts' questionnaire to differentiate between early and late dumping. Insulin and glucose levels were also measured.

RESULTS:

Sigstad score remained significantly elevated at 6 and 12 months postoperatively compared to preoperative values. Symptoms suggestive of dumping syndrome were recorded in 40 % of patients at 6 months and in 33 % at 12 months postoperatively. Arts' questionnaire demonstrated that early dumping score remained higher compared to baseline at 6 and 12 months postoperatively. Late dumping scores increased gradually during the time and that difference was statistically significant at 12 months after LSG. Hypoglycaemia occurred at 33 % of patients both at 6 and 12 months postoperatively.

CONCLUSIONS:

Symptoms suggestive of dumping syndrome after provocation still exist at 6 and 12 months in a significant proportion of patients after LSG and include both early and late dumping. These findings are consistent with the high incidence of hypoglycaemia after OGTT at 6 and 12 months after LSG.

• Authors: Dimitris Papamargaritis, George Koukoulis, Eleni Sioka, Eleni Zachari, Alexandra Bargiota, Dimitris Zacharoulis, George Tzovaras
• Journal: Obesity surgery (Obes Surg) Vol. 22 Issue 10 Pg. 1600-6 (Oct 2012) ISSN: 1708-0428 [Electronic] United States
• PMID: 22773085 (Publication Type: Journal Article)

Topics

• Adult
• Body Mass Index
• Dumping Syndrome (epidemiology, etiology, physiopathology)
• Feeding Behavior
• Female
• Follow-Up Studies
• Gastroplasty (adverse effects, methods)
• Glucose Tolerance Test
• Humans
• Hypoglycemia (epidemiology, etiology, physiopathology)
• Incidence
• Laparoscopy
• Male
• Obesity, Morbid (complications, physiopathology, surgery)
• Surveys and Questionnaires
• Time Factors
• Treatment Outcome