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Crotalidae polyvalent immune Fab: a guide to its use in North American crotaline envenomation.

Abstract
Intravenous crotalidae polyvalent immune Fab (CroFab(®)) is effective in patients with minimal, moderate or severe crotaline envenomation, halting the progression of local venom effects and ameliorating haematological and other systemic abnormalities of envenomation. Despite treatment, patients may experience delayed-onset or recurrent venom effects (e.g. coagulopathy). Intravenous crotalidae polyvalent immune Fab is generally well tolerated, with acute hypersensitivity reactions being the most commonly occurring adverse event.
AuthorsGillian M Keating, Katherine A Lyseng-Williamson
JournalClinical drug investigation (Clin Drug Investig) Vol. 32 Issue 8 Pg. 555-60 (Aug 01 2012) ISSN: 1179-1918 [Electronic] New Zealand
PMID22765769 (Publication Type: Journal Article)
Chemical References
  • Immunoglobulin Fab Fragments
Topics
  • Humans
  • Immunoglobulin Fab Fragments (immunology)
  • North America
  • Snake Bites

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