Abstract |
The authors report the case of a 20-year-old man who presented with a de novo episode of hypomania subsequent to the initiation of quinacrine for treatment resistant giardiasis. The hypomanic episode commenced some 20 days after the successful completion of a week long course of quinacrine 100 mg three times daily. The hypomanic episode was treated with olanzapine 10 mg daily. Two months subsequent to this, the patient developed a moderate depressive episode which was treated with escitalopram and olanzapine. One month after the resolution of the depressive episode, he once again presented with a hypomanic episode. The recurring episodes of discrete mood disturbance all occurred within 5 months of the commencement of quinacrine in an individual with no personal history of affective disorders.
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Authors | John Lally, Fintan Byrne, Elizabeth Walsh |
Journal | BMJ case reports
(BMJ Case Rep)
Vol. 2012
(Jun 21 2012)
ISSN: 1757-790X [Electronic] England |
PMID | 22729334
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Antiprotozoal Agents
- Quinacrine
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Topics |
- Adult
- Antiprotozoal Agents
(adverse effects)
- Bipolar Disorder
(chemically induced, diagnosis, drug therapy)
- Giardiasis
(drug therapy)
- Humans
- Male
- Quinacrine
(adverse effects)
- Young Adult
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