HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

[Differences between species involved and fluoroquinolone resistance patterns of strains isolated from bacteriuria according to nosocomial, health-related or community-acquired onset].

AbstractPURPOSE:
To describe and to compare species and antibiotics resistance patterns of bacteria involved among bacteriuria from hospital and city laboratories and among health-related and community-acquired bacteriuria.
METHODS:
Epidemiologic transversal study conducted among Bacteriology laboratories of University Hospital (UH) and the whole city of Reims, during the week 21 to 26 June 2010. A standardized investigation form was completed after telephonical interview with the prescriber.
RESULTS:
One hundred and eighty-nine strains have been isolated among 179 urocultures. One hundred and seven strains were isolated in city laboratories and 82 in UH laboratory. Strains were community-acquired, health-related and nosocomial in 136, 22 and 31 cases, respectively. More Gram positive bacteria and ofloxacin resistant strains were isolated among UH strains (P=0.001 and P=0.015, respectively) and among health-related strains (P=0.01 and P=0.003, respectively). When analysis was restricted only to Enterobacteriaceae or to Escherichia coli, the ofloxacin resistance rate was no more elevated among health-related or UH strains. Ofloxacin resistant Enterobacteriaceae were more frequently resistant to all other classes of antibiotics except nitrofurans.
DISCUSSION:
Strains isolated in health-related bacteriuria are more frequently ofloxacin resistant principally because of the greater proportion of Gram positive bacteria and because of a non-significant higher ofloxacin resistance rate among Enterobacteriaceae. Numerous studies only focus on Enterobacteriaceae, and the data from our study need to be confirmed on larger samples, in order to validate the predictive value of health-related bacteriuria for ofloxacin resistance.
AuthorsJérome Tassain, Yohan N'Guyen, Anne-Sophie Batalla, Véronique Duval, Thomas Guillard, Christophe De Champs, Christophe Strady
JournalPresse medicale (Paris, France : 1983) (Presse Med) Vol. 41 Issue 12 Pt 1 Pg. e586-93 (Dec 2012) ISSN: 2213-0276 [Electronic] France
Vernacular TitleDifférences d'espèces en cause et de résistance aux fluoroquinolones des souches isolées dans les bactériuries selon leur caractère nosocomial, lié au soin ou communautaire.
PMID22727916 (Publication Type: Comparative Study, English Abstract, Journal Article)
CopyrightCopyright © 2012. Published by Elsevier Masson SAS.
Chemical References
  • Anti-Bacterial Agents
  • Ofloxacin
Topics
  • Anti-Bacterial Agents (pharmacology, therapeutic use)
  • Bacteriuria (drug therapy, microbiology)
  • Community-Acquired Infections (drug therapy, microbiology)
  • Cross Infection (drug therapy, microbiology)
  • Drug Resistance, Bacterial
  • Gram-Negative Bacteria (drug effects)
  • Gram-Positive Bacteria (drug effects)
  • Humans
  • Ofloxacin (pharmacology, therapeutic use)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: