Abstract | INTRODUCTION: AREAS COVERED: The aim of this paper is to review the experience accumulated with indapamide. It is limited to clinical studies that are relevant for the everyday management of hypertensive patients, whether or not they exhibit cardiovascular or renal disease. EXPERT OPINION:
Indapamide, because of its well-documented beneficial effects on cardiovascular and renal outcomes, represents a safe and valuable option for treating patients with high BP. There is, however, still room for new trials evaluating the combination of this diuretic with other types of antihypertensive drugs, in particular a calcium antagonist such as amlodipine. There is also the need to compare the indapamide- perindopril and indapamide- amlodipine combinations, in terms of antihypertensive efficacy, tolerability and effects on target organ damage and, ideally, on cardiovascular mortality.
|
Authors | Bernard Waeber, Corina Rotaru, François Feihl |
Journal | Expert opinion on pharmacotherapy
(Expert Opin Pharmacother)
Vol. 13
Issue 10
Pg. 1515-26
(Jul 2012)
ISSN: 1744-7666 [Electronic] England |
PMID | 22725706
(Publication Type: Journal Article, Review)
|
Chemical References |
- Antihypertensive Agents
- Diuretics
- Vasodilator Agents
- Indapamide
|
Topics |
- Antihypertensive Agents
(therapeutic use)
- Diuretics
(therapeutic use)
- Humans
- Hypertension
(drug therapy, metabolism)
- Indapamide
(therapeutic use)
- Vasodilator Agents
(therapeutic use)
|