Trigeminal postherpetic neuralgia responsive to treatment with capsaicin 8 % topical patch: a case report.

Postherpetic neuralgia has been variably defined but is generally understood to be pain that persists for longer than a few months after an attack of herpes zoster. Pain persists for years in approximately 10 % of those afflicted with acute herpes zoster. The likelihood of postherpetic neuralgia increases with older age, severity of the zoster, trigeminal location, and other factors. Postherpetic neuralgia is a neuropathic pain and treatment usually involves sequential trials of topical and systemic drugs; a variety of other therapies may be considered in refractory cases. A new topical capsaicin 8 % patch has been approved for this indication based on the positive studies in patients with non-trigeminal postherpetic neuralgia. Experience with the use of the capsaicin 8 % patch for trigeminal distribution neuralgia is lacking. We report a case of trigeminal postherpetic neuralgia which was safely and effectively treated with capsaicin 8 % patch.
AuthorsJennifer Sayanlar, Nilufer Guleyupoglu, Russell Portenoy, Sait Ashina
JournalThe journal of headache and pain (J Headache Pain) Vol. 13 Issue 7 Pg. 587-9 (Oct 2012) ISSN: 1129-2377 [Electronic] Italy
PMID22717586 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Sensory System Agents
  • Capsaicin
  • Administration, Topical
  • Capsaicin (administration & dosage)
  • Female
  • Humans
  • Middle Aged
  • Neuralgia, Postherpetic (drug therapy)
  • Sensory System Agents (administration & dosage)
  • Trigeminal Neuralgia (drug therapy, etiology)

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