Successful treatment of pyoderma gangrenosum with intravenous immunoglobulins during pregnancy.

Abstract

BACKGROUND:

Pyoderma gangrenosum is a rare ulcerative skin disease usually starting with a pustular lesion that rapidly progresses to painful ulcers with undermined violaceous borders. Numerous associated disorders have been described, including inflammatory bowel disease, rheumatologic or hematologic disorders, chronic active hepatitis, and malignancies. The occurrence of pyoderma gangrenosum during pregnancy is uncommon.

OBJECTIVE:

We report a case of a patient with an aggravation of preknown pyoderma gangrenosum during pregnancy who was successfully treated with intravenous immunoglobulins.

CONCLUSION:

Administration of immunoglobulins represents a safe and effective treatment option for this subset of patients, as demonstrated in the present case.

• Authors: Cornelia Erfurt-Berge, Christine Herbst, Gerold Schuler, Juergen Bauerschmitz
• Journal: Journal of cutaneous medicine and surgery (J Cutan Med Surg) 2012 May-Jun Vol. 16 Issue 3 Pg. 205-7 ISSN: 1203-4754 [Print] United States
• PMID: 22713447 (Publication Type: Case Reports, Journal Article)

Chemical References

• Immunoglobulins, Intravenous

Topics

• Adult
• Female
• Humans
• Immunoglobulins, Intravenous (therapeutic use)
• Pregnancy
• Pregnancy Complications (drug therapy)
• Pyoderma Gangrenosum (drug therapy)