Refractory Salmonella enterica serotype choleraesuis-related renal cyst infection in a patient with autosomal dominant polycystic kidney disease undergoing hemodialysis treated successfully with intracystic ciprofloxacin infusion.

Abstract

OBJECTIVE:

To report a potential salvage therapy for refractory renal cyst infection secondary to Salmonellaenterica serotype choleraesuis (S. choleraesuis).

CLINICAL PRESENTATION AND INTERVENTION:

A 52-year-old male with autosomal dominant polycystic kidney disease undergoing hemodialysis experienced an episode of S. choleraesuis-related gastroenteritis subsequently complicated by bloodstream and refractory renal cyst infection with formation of multiple pyocysts. The patient was treated with intracystic indwelling diluted ciprofloxacin solution.

CONCLUSION:

In this patient, intracystic infusion of ciprofloxacin achieved a sufficient antibiotic level in infected renal cysts and hence completely eradicated S. choleraesuis. Therefore, intracystic antiobiotic infusion could be a potential salvage therapy for refractory renal cyst infection.

• Authors: Chih-Chao Yang, Feng-Rong Chuang, Chien-Hsing Wu, Jin-Bor Chen, Chih-Hsiung Lee, Chien-Te Lee
• Journal: Medical principles and practice : international journal of the Kuwait University, Health Science Centre (Med Princ Pract) Vol. 21 Issue 6 Pg. 576-8 ( 2012) ISSN: 1423-0151 [Electronic] Switzerland
• PMID: 22710499 (Publication Type: Case Reports, Journal Article)
• Copyright: Copyright © 2012 S. Karger AG, Basel.

Chemical References

• Anti-Infective Agents
• Ciprofloxacin

Topics

• Anti-Infective Agents (therapeutic use)
• Ciprofloxacin (administration & dosage, therapeutic use)
• Cysts (diagnosis, drug therapy, microbiology)
• Gastroenteritis (complications)
• Humans
• Male
• Middle Aged
• Polycystic Kidney, Autosomal Dominant (complications, therapy)
• Renal Dialysis
• Salmonella Infections (diagnosis, drug therapy, etiology)
• Salmonella enterica (isolation & purification)
• Treatment Outcome