¹H, ¹³C, ¹⁵N backbone and side-chain resonance assignments of the human adenylate kinase 1 in apo form.

Abstract

AK1 (Adenylate Kinase 1) plays crucial roles in processes such as cellular phosphotransfer networks, neuronal maturation and regeneration, gating of ABC transporter CFTR, tumor cell metabolism and myocardial energetic homeostasis. Here we report (1)H, (15)N and (13)C backbone and side-chain resonance assignments of the human AK1 protein in apo form. This work lays the essential basis for the further structure determination of hAK1.

• Authors: Cuiping Fu, Yu Peng, Xinli Liao, Chenyun Guo, Donghai Lin
• Journal: Biomolecular NMR assignments (Biomol NMR Assign) Vol. 7 Issue 2 Pg. 155-8 (Oct 2013) ISSN: 1874-270X [Electronic] Netherlands
• PMID: 22706932 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Apoenzymes
• Carbon Isotopes
• Nitrogen Isotopes
• Protons
• Adenylate Kinase
• adenylate kinase 1

Topics

• Adenylate Kinase (chemistry)
• Apoenzymes (chemistry)
• Carbon Isotopes
• Humans
• Nitrogen Isotopes
• Nuclear Magnetic Resonance, Biomolecular
• Protein Structure, Secondary
• Protons