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[Isolated prolongation of the PTT: 2-year retrospective study].

Abstract
The hemorrhagic risk associated with isolated prolongation of the PTT has been evaluated in a 2-year retrospective study. Of the 60 cases thus found, a hemorrhagic risk was present in 15 patients of whom 7 had hemophilia A, 5 von Willebrand's disease and 3 factor XI deficiency. Among the other etiologies not associated with a bleeding tendency, there were 31 proved or suspected cases with inhibitors of the PTT, most of whom were children, 2 factor XII deficiencies, 2 prekallikrein deficiencies and 4 contact phase activations. Isolated prolongation of the PTT is therefore without specificity and needs further investigation of hemostasis to determine the associated hemorrhagic risk.
AuthorsG Michel-Reymond, H Knecht, J Hauert, F Bachmann
JournalSchweizerische medizinische Wochenschrift (Schweiz Med Wochenschr) Vol. 120 Issue 50 Pg. 1939-41 (Dec 15 1990) ISSN: 0036-7672 [Print] Switzerland
Vernacular TitleAllongement isolé du PTT: étude rétrospective sur 2 ans.
PMID2270449 (Publication Type: English Abstract, Journal Article)
Topics
  • Factor XI Deficiency (blood)
  • Hematologic Diseases (blood)
  • Hemophilia A (blood)
  • Hemorrhage (blood)
  • Humans
  • Prothrombin Time
  • Retrospective Studies
  • Risk Factors
  • von Willebrand Diseases (blood)

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