Abstract |
The hemorrhagic risk associated with isolated prolongation of the PTT has been evaluated in a 2-year retrospective study. Of the 60 cases thus found, a hemorrhagic risk was present in 15 patients of whom 7 had hemophilia A, 5 von Willebrand's disease and 3 factor XI deficiency. Among the other etiologies not associated with a bleeding tendency, there were 31 proved or suspected cases with inhibitors of the PTT, most of whom were children, 2 factor XII deficiencies, 2 prekallikrein deficiencies and 4 contact phase activations. Isolated prolongation of the PTT is therefore without specificity and needs further investigation of hemostasis to determine the associated hemorrhagic risk.
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Authors | G Michel-Reymond, H Knecht, J Hauert, F Bachmann |
Journal | Schweizerische medizinische Wochenschrift
(Schweiz Med Wochenschr)
Vol. 120
Issue 50
Pg. 1939-41
(Dec 15 1990)
ISSN: 0036-7672 [Print] Switzerland |
Vernacular Title | Allongement isolé du PTT: étude rétrospective sur 2 ans. |
PMID | 2270449
(Publication Type: English Abstract, Journal Article)
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Topics |
- Factor XI Deficiency
(blood)
- Hematologic Diseases
(blood)
- Hemophilia A
(blood)
- Hemorrhage
(blood)
- Humans
- Prothrombin Time
- Retrospective Studies
- Risk Factors
- von Willebrand Diseases
(blood)
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