HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Use of Suprathel® for partial thickness burns in children.

Abstract
We evaluated the use of Suprathel(®), a synthetic skin substitute, for partial thickness burns in children. Thirty-three children (20 females, 13 males; mean age 29 months, range 5 months to 11 years) with burns were treated with Suprathel(®). The burns were superficial partial thickness (n=24) or mid-dermal (n=19); the median %TBSA was 4% (range 1-13%). Suprathel(®) was applied after debridement, followed by Vaseline gauze, dry gauze and crepe bandage. The outer dressings were changed every 5-10 days unless clinical problems dictated otherwise. Median healing time was 16 days (range 9-38 days). Ten patients took longer than 21 days to heal, of whom four developed hypertrophic scarring, which was strongly associated with wound infection (p<0.05). Healing time of superficial partial thickness and mid-dermal burns was not significantly different (p=0.494). Suprathel(®) is an effective skin substitute for the treatment of partial thickness burns in children. The majority of burns in children are mixed depth, and Suprathel(®) has the advantage that it may also be used to treat mid-dermal burns. It behaves like a biological dressing but is not animal derived, so is acceptable to all religious and ethnic groups. Further studies to evaluate the efficacy and cost effectiveness of Suprathel(®) compared to other dressings in children are warranted.
AuthorsLyndsey Highton, Christopher Wallace, Mamta Shah
JournalBurns : journal of the International Society for Burn Injuries (Burns) Vol. 39 Issue 1 Pg. 136-41 (Feb 2013) ISSN: 1879-1409 [Electronic] Netherlands
PMID22698841 (Publication Type: Journal Article)
CopyrightCopyright © 2012 Elsevier Ltd and ISBI. All rights reserved.
Chemical References
  • Polyesters
  • poly(lactide-co-trimethylenecarbonate-co-epsilon-caprolactone)
Topics
  • Burns (pathology, therapy)
  • Child
  • Child, Preschool
  • Debridement
  • Female
  • Humans
  • Infant
  • Male
  • Polyesters (therapeutic use)
  • Skin Transplantation (methods)
  • Skin, Artificial
  • Wound Healing

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: