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Risk of underdiagnosing amebic dysentery due to false-negative Entamoeba histolytica antigen detection.

Abstract
Entamoeba histolytica antigen assays on stool are widely used to diagnose amebiasis. We report a case of confirmed amebic colitis with a false-negative antigen detection that became positive after treatment. Our results indicate that these assays may underdiagnose acute amebic infection when used alone and should be used cautiously.
AuthorsNúria Prim, Pilar Escamilla, Roser Solé, Teresa Llovet, Germán Soriano, Carmen Muñoz
JournalDiagnostic microbiology and infectious disease (Diagn Microbiol Infect Dis) Vol. 73 Issue 4 Pg. 372-3 (Aug 2012) ISSN: 1879-0070 [Electronic] United States
PMID22683092 (Publication Type: Case Reports, Journal Article)
CopyrightCopyright © 2012 Elsevier Inc. All rights reserved.
Chemical References
  • Antigens, Protozoan
Topics
  • Adult
  • Antigens, Protozoan (analysis)
  • Diagnostic Errors
  • Dysentery, Amebic (diagnosis)
  • Entamoeba histolytica (immunology, isolation & purification)
  • Feces (chemistry, parasitology)
  • Humans
  • Male
  • Microscopy

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