Abstract | AIM: METHODS: RESULTS: Serum fT3 had positive correlations with body mass index (BMI), body fat mass (BFM), total body water (TBW) and intracellular water (ICW), and negative correlations with the ratio of extracellular water to total body water (ECW/TBW) and hANP. There were no correlations between serum fT4 and any body composition parameter. The 49 patients with data at baseline and after 1 year were divided into groups with increased (n = 33) and decreased (n = 16) fT3 after 1 year. ΔBMI and ΔBFM were significantly lower and ΔTBW, ΔICW, ΔECW and ΔECW/TBW (changes over 1 year from baseline) were significantly higher in patients with decreased fT3 compared to those with increased fT3. There was no significant difference in ΔhANP or Δcardiothoracic ratio between the two groups. CONCLUSION: These results show that a decrease in fT3 might be associated with emaciation and interstitial edema in Japanese hemodialysis patients.
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Authors | Osamu Saito, Takako Saito, Koshi Ueno, Takeshi Shiraishi, Takanori Kikuchi, Hisashi Yamamoto, Tetsu Akimoto, Yasuhiro Ando, Shigeaki Muto, Eiji Kusano |
Journal | Clinical and experimental nephrology
(Clin Exp Nephrol)
Vol. 16
Issue 6
Pg. 952-8
(Dec 2012)
ISSN: 1437-7799 [Electronic] Japan |
PMID | 22678525
(Publication Type: Comparative Study, Journal Article)
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Chemical References |
- Triiodothyronine
- Atrial Natriuretic Factor
- Thyroxine
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Topics |
- Adult
- Aged
- Aged, 80 and over
- Atrial Natriuretic Factor
(blood)
- Body Composition
(physiology)
- Body Fluids
(metabolism)
- Body Mass Index
- Body Water
(metabolism)
- Edema
(metabolism)
- Emaciation
(metabolism)
- Female
- Humans
- Intracellular Fluid
(metabolism)
- Japan
- Kidney Failure, Chronic
(metabolism, therapy)
- Male
- Middle Aged
- Renal Dialysis
- Retrospective Studies
- Thyroxine
(blood)
- Triiodothyronine
(blood)
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