Abstract |
Blocking efficacy and acute toxicity of prilocaine (15 ml of 10 mg/ml prilocaine) was examined in 35 (16 + 19) patients by using blocks of the radial, ulnar and median nerves in the elbow region (Group 1), or the haematoma block method (Group 2) for the manipulation of Colles' fracture. In Group 1 vs Group 2, the reposition was painless in 44% (7/16) vs 68% (13/19), moderate pain occurred in 38% (6/16) vs 21% (4/19), and severe pain in 19% (3/16) vs 11% (2/19). At 15 minutes there was a higher degree of block, on average, at the median and ulnar nerve innervation areas in Group 1. Complete motor block at peripheral innervation regions of all three nerves was achieved in only one patient in Group 1 and in no case in Group 2. Despite this, the surgeons assessed the relaxation at the wrist satisfactory for reposition of the fracture in all but one patient (Group 2). The highest individual prilocaine plasma concentration in Group 1 was 0.68 microgram/ml at ten minutes, whereas the highest individual value in Group 2 was 0.77 microgram/ml at ten minutes. Systemic toxicity from the local anaesthetic did not occur.
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Authors | J Haasio |
Journal | Annales chirurgiae et gynaecologiae
(Ann Chir Gynaecol)
Vol. 79
Issue 3
Pg. 168-71
( 1990)
ISSN: 0355-9521 [Print] Finland |
PMID | 2264720
(Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial)
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Chemical References |
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Topics |
- Aged
- Anesthesia, Local
- Colles' Fracture
(therapy)
- Female
- Humans
- Male
- Median Nerve
- Middle Aged
- Nerve Block
- Prilocaine
(administration & dosage, blood)
- Radial Nerve
- Time Factors
- Ulnar Nerve
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