Prevention of coccidiosis in the chukar partridge (Alectoris chukar) by medication with sulfadimethoxine and ormetoprim (Rofenaid).

Abstract

Rofenaid (a 5:3 mixture of sulfadimethoxine and ormetoprim) was effective in preventing coccidiosis of chukar partridges. Levels of .0100 or .0125% sulfadimethoxine, with the corresponding level of ormetoprim in the ration, gave the best results. These levels markedly reduced mortality in severe infections (over 75% mortality in unmedicated chukars) and eliminated mortality in medicated groups when infections produced 52% mortality or less in unmedicated controls. In the latter infections, Rofenaid also protected against the depression in weight gain seen 6 days postinoculation in unmedicated chukars. Studies in uninoculated chukars showed that Rofenaid has a wide safety margin and did not produce adverse effects even at levels of .0300% sulfadimethoxine. Rofenaid should, therefore, be an effective medication for the prevention of coccidiosis in chukars in the field. Data from the present studies are being submitted to the IR-4 Program of the Food and Drug Administration for consideration of approval for the use of Rofenaid in chukar partridges.

• Authors: M D Ruff, G C Wilkins
• Journal: Poultry science (Poult Sci) Vol. 69 Issue 10 Pg. 1675-80 (Oct 1990) ISSN: 0032-5791 [Print] England
• PMID: 2263542 (Publication Type: Journal Article)

Chemical References

• Anti-Infective Agents
• Drug Combinations
• Pyrimidines
• ormetoprim, sulfadimethoxine drug combination
• Sulfadimethoxine

Topics

• Animal Feed
• Animals
• Anti-Infective Agents (adverse effects, therapeutic use)
• Body Weight (drug effects)
• Coccidiosis (prevention & control, veterinary)
• Drug Combinations
• Poultry
• Poultry Diseases (prevention & control)
• Pyrimidines (adverse effects, therapeutic use)
• Sulfadimethoxine (adverse effects, therapeutic use)