[Strontium chloride (89Sr-chloride) fractional injection method for bone metastases treatment].

Abstract

The study was designed to compare the effectivnes of 89Sr-chlorid injections by 50 Mbk fractions with standard 150 Mbk injection in patients with bone metastases. Fifty patients with bone metastases were included in the study, 25 of them received 89Sr-chloride by fractional and 25 (control group) by single injection. The pain intensity, white blood cells and thrombocytes concentration values were evaluated in both groups before and after treatment. The study proved the possibility of using systemic 89Sr-chloride fractional radiotherapy in patients with bone metastases and concurrent stage 2-3 myelosupression. The method of fractial 89Sr-chloride injection is effective in symptomatic treatment of patients with bone metastases.

• Authors: D K Fomin, Iu N Smirnov, O B Tararukhina, A A Nazarov
• Journal: Voprosy onkologii (Vopr Onkol) Vol. 58 Issue 1 Pg. 116-8 ( 2012) ISSN: 0507-3758 [Print] Russia (Federation)
• PMID: 22629840 (Publication Type: Case Reports, Controlled Clinical Trial, Journal Article)

Chemical References

• Strontium Radioisotopes
• strontium chloride
• Strontium

Topics

• Aged
• Aged, 80 and over
• Bone Neoplasms (drug therapy, radiotherapy, secondary)
• Dose Fractionation, Radiation
• Female
• Humans
• Injections
• Leukocyte Count
• Middle Aged
• Pain (etiology)
• Pain Measurement
• Platelet Count
• Strontium (therapeutic use)
• Strontium Radioisotopes (therapeutic use)
• Treatment Outcome