Abstract | BACKGROUND:
Sporotrichosis is a subcutaneous fungal infection caused by a thermally dimorphic aerobic fungus, Sporothrix schenckii. It results from traumatic inoculation or contact with animals. Most cases were reported mainly in the tropics and subtropics. OBJECTIVE: The objective of our study is to assess the clinical characteristic of cutaneous sporotrichosis among our patients. METHODOLOGY: We performed a retrospective review of all cases diagnosed with cutaneous sporotrichosis from July 2004 to June 2010. Patients' medical records were retrieved and analyzed according to demography, preceding trauma, sites of lesions, clinical subtypes, treatment, and clinical response. RESULTS: Nineteen cases were diagnosed with cutaneous sporotrichosis with a male/female ratio of 9:10. Thirteen cases (68.4%) were able to recall preceding trauma, and seven of them reported cat scratches or cat bites. Lymphocutaneous sporotrichosis was observed in 13 cases (68.4%) followed by four cases of fixed cutaneous sporotrichosis and two cases of disseminated sporotrichosis. Histologically, 11 cases (57.8%) demonstrated a granulomatous reaction. Sporothrix schenckii was cultured in 12 cases (63.2%). Thirteen cases (68.4%) were successfully treated with oral itraconazole alone for a mean duration of 15.6 weeks. Two cases with disseminated cutaneous sporotrichosis were treated with intravenous amphotericin B. CONCLUSION:
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Authors | Min Moon Tang, Jyh Jong Tang, Priya Gill, Choong Chor Chang, Roshidah Baba |
Journal | International journal of dermatology
(Int J Dermatol)
Vol. 51
Issue 6
Pg. 702-8
(Jun 2012)
ISSN: 1365-4632 [Electronic] England |
PMID | 22607289
(Publication Type: Journal Article)
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Copyright | © 2012 The International Society of Dermatology. |
Chemical References |
- Antifungal Agents
- Itraconazole
- Amphotericin B
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Topics |
- Adult
- Aged
- Amphotericin B
(therapeutic use)
- Animals
- Antifungal Agents
(therapeutic use)
- Bites and Stings
(complications)
- Cats
(microbiology)
- Child
- Female
- Humans
- Itraconazole
(therapeutic use)
- Malaysia
- Male
- Middle Aged
- Retrospective Studies
- Sporothrix
(isolation & purification)
- Sporotrichosis
(diagnosis, drug therapy, etiology)
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