Abstract | OBJECTIVE: To evaluate the efficacy of a plant-derived wound dressing, a mixture of hypericum oil (Hypericum perforatum) and neem oil (Azadirachta indica), in scalp wounds with exposed bone. METHOD: A retrospective review was conducted of all patients presenting with scalp wounds with exposed bone following the excision of skin tumours and treated with a plant-derived wound dressings (1 Primary Wound Dressing; Phytoceuticals AG), from January to July 2011. Time to healing, wound size, area of exposed bone, ease of handling, pain and complications were evaluated. RESULTS: Nine consecutive patients were analysed retrospectively. The patients' mean age was 81.2 ± 8.5 years (63-90 years), with a mean wound size of 13.2 ± 6.8cm(2) (0.4-22.6cm(2)) and 6.8 ± 6.5cm(2) (0.3-20.7cm(2)) of exposed bone. The time to complete healing by secondary intention was 4-20 weeks. A rapid induction of granulation tissue was observed, which covered the entire exposed bone surface in six out of nine cases (67%) after 4 weeks, and showed a reduction in the mean area of exposed bone of 95%. Dressing change was easy and without pain and there were no complications. CONCLUSION: This retrospective, non-controlled analysis suggests that ONE is a very simple to use, safe and potentially effective therapy for the treatment of scalp wounds with exposed bone. DECLARATION OF INTEREST: There were no external sources of funding for this study. The authors have no conflict of interest to declare.
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Authors | S Läuchli, J Hafner, C Wehrmann, L E French, T Hunziker |
Journal | Journal of wound care
(J Wound Care)
Vol. 21
Issue 5
Pg. 228, 230, 232-3
(May 2012)
ISSN: 0969-0700 [Print] England |
PMID | 22584740
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Aged
- Aged, 80 and over
- Azadirachta
- Drug Therapy, Combination
- Female
- Head and Neck Neoplasms
(surgery)
- Humans
- Hypericum
- Middle Aged
- Phytotherapy
- Plant Oils
(therapeutic use)
- Postoperative Complications
(drug therapy)
- Scalp
(injuries)
- Skin Neoplasms
(surgery)
- Skull
- Wounds, Nonpenetrating
(drug therapy)
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