Lichen planus induced by carbamazepine: a case report.

Abstract

We report a case of Lichen planus in a female patient who has been treated for epilepsy in the Referral Center for Epilepsy of the Ministry of Health of the Republic of Croatia. She was diagnosed with mesio-temporal lobe epilepsy with secondary generalization and had been treated for years with carbamazepine. In Novemeber 2009, erythematous papulosquamous papules were noticed on her trunk and under her breasts which spread to her legs. Dermatohistological testing confirmed the diagnosis of Lichen planus. Replacement of carbamazepine with oxcarbazepine and application of steroid therapy resulted in regression of skin changes.

• Authors: S Hajnsek, V Milavec-Puretic, S Nankovic, Z Petelin Gadze, I Filipcic, A Bujan Kovac, D Stulhofer Buzina
• Journal: Epilepsy & behavior : E&B (Epilepsy Behav) Vol. 24 Issue 2 Pg. 269-71 (Jun 2012) ISSN: 1525-5069 [Electronic] United States
• PMID: 22564889 (Publication Type: Case Reports, Journal Article)
• Copyright: Copyright © 2012 Elsevier Inc. All rights reserved.

Chemical References

• Anti-Inflammatory Agents
• Anticonvulsants
• Carbamazepine
• Betamethasone
• Oxcarbazepine

Topics

• Administration, Topical
• Aged
• Anti-Inflammatory Agents (administration & dosage, therapeutic use)
• Anticonvulsants (adverse effects, therapeutic use)
• Betamethasone (administration & dosage, therapeutic use)
• Carbamazepine (administration & dosage, adverse effects, analogs & derivatives, therapeutic use)
• Craniocerebral Trauma (complications)
• Epilepsy, Generalized (complications, drug therapy)
• Epilepsy, Temporal Lobe (complications, drug therapy)
• Female
• Humans
• Lichen Planus (chemically induced, drug therapy, pathology)
• Oxcarbazepine
• Skin (pathology)