Thin-layer chromatography of urinary neutral oligosaccharides: the detection of blood group-related oligosaccharides and screening for lysosomal storage disease.

Abstract

We devised an improved technique of thin layer chromatography, which permitted the high resolution of urinary neutral oligosaccharides and the qualitative determination of blood group related oligosaccharides as well as oligosaccharides pathologically secreted in lysosomal storage diseases. This procedure can be used inscreening for disorders associated with abnormal excretion of oligosaccharides, as well as in the purification of oligosaccharides.

• Authors: M Kuriyama, R Hiwatari, A Igata
• Journal: The Tohoku journal of experimental medicine (Tohoku J Exp Med) Vol. 161 Issue 4 Pg. 335-41 (Aug 1990) ISSN: 0040-8727 [Print] Japan
• PMID: 2256107 (Publication Type: Journal Article)

Chemical References

• ABO Blood-Group System
• Antigens
• Blood Group Antigens
• Lewis Blood Group Antigens
• Oligosaccharides

Topics

• ABO Blood-Group System (immunology)
• Adolescent
• Adult
• Antigens (urine)
• Blood Group Antigens (immunology)
• Carbohydrate Sequence
• Chromatography, Thin Layer (methods)
• Humans
• Lewis Blood Group Antigens (immunology)
• Mass Screening
• Metabolism, Inborn Errors (prevention & control, urine)
• Molecular Sequence Data
• Oligosaccharides (chemistry, immunology, urine)