Abstract | OBJECT: METHODS: A retrospective cohort was compiled using the 2006 Kids' Inpatient Database to identify children younger than 21 years of age who underwent intracranial neoplasm resection. Hyponatremia was ascertained by diagnosis codes. Bivariate analyses were conducted using chi-square and Mann-Whitney U-tests. Logistic regression models were developed to evaluate factors associated with hyponatremia in bivariate analyses. RESULTS: CONCLUSIONS:
Hyponatremia commonly occurs with resection of intracranial malignant tumors, especially for lesions located in the deep brain and in patients with obstructive hydrocephalus. Hyponatremia was associated with higher morbidity. Further research is needed to develop targeted monitoring and intervention strategies to decrease perioperative hyponatremia and to determine if this could decrease the number of complications in this specialized population.
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Authors | Cydni Williams, Tamara D Simon, Jay Riva-Cambrin, Susan L Bratton |
Journal | Journal of neurosurgery. Pediatrics
(J Neurosurg Pediatr)
Vol. 9
Issue 5
Pg. 524-9
(May 2012)
ISSN: 1933-0715 [Electronic] United States |
PMID | 22546031
(Publication Type: Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)
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Topics |
- Adolescent
- Algorithms
- Brain Neoplasms
(economics, surgery)
- Child
- Child, Preschool
- Cohort Studies
- Data Interpretation, Statistical
- Databases, Factual
- Female
- Humans
- Hydrocephalus
(complications)
- Hyponatremia
(economics, epidemiology, etiology)
- Infant
- Infant, Newborn
- International Classification of Diseases
- Length of Stay
- Logistic Models
- Magnetic Resonance Imaging
- Male
- Models, Statistical
- Neurosurgical Procedures
(adverse effects, economics)
- Postoperative Complications
(economics, epidemiology, etiology)
- Respiration, Artificial
(statistics & numerical data)
- Retrospective Studies
- Risk Factors
- Sepsis
(complications)
- United States
(epidemiology)
- Ventriculoperitoneal Shunt
- Ventriculostomy
- Young Adult
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