Abstract | OBJECTIVE: HPV can infect cells of epithelial origin and is closely associated with carcinomas. Studies investigating its presence in salivary gland neoplasms are few and conflicting. METHODS: Detection of HPV types 16 & 18 was done on 34 formalin-fixed, paraffin-embedded archival material of different salivary gland neoplasms using Digene HPV types 16 & 18 probe using in situ hybridization technique. RESULTS: CONCLUSIONS: An association exists between HPV infections and salivary gland neoplasms. However, given the sparse pattern of reactive cells, it cannot be confirmed that this virus is implicated in the aetiology of this group of tumours.
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Authors | Layla Hafed, Heba Farag, Olfat Shaker, Dalia El-Rouby |
Journal | Archives of oral biology
(Arch Oral Biol)
Vol. 57
Issue 9
Pg. 1194-9
(Sep 2012)
ISSN: 1879-1506 [Electronic] England |
PMID | 22542162
(Publication Type: Journal Article)
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Copyright | Copyright © 2012 Elsevier Ltd. All rights reserved. |
Chemical References |
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Topics |
- Adenolymphoma
(virology)
- Adenoma, Pleomorphic
(virology)
- Adult
- Aged
- Aged, 80 and over
- Carcinoma, Adenoid Cystic
(virology)
- Carcinoma, Mucoepidermoid
(virology)
- DNA Probes
- DNA, Viral
(analysis)
- Epithelial Cells
(virology)
- Female
- Human papillomavirus 16
(isolation & purification)
- Human papillomavirus 18
(isolation & purification)
- Humans
- In Situ Hybridization
- Lymphoma
(virology)
- Male
- Middle Aged
- Myoepithelioma
(virology)
- Papillomavirus Infections
(virology)
- Salivary Gland Neoplasms
(virology)
- Young Adult
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