Honey is one of the oldest substances used in
wound management. Efficacy of Gelam honey in wound healing was evaluated in this paper. Sprague-Dawley rats were randomly divided into four groups of 24 rats each (untreated group, saline group,
Intrasite Gel group, and Gelam honey group) with 2 cm by 2 cm full thickness, excisional
wound created on neck area.
Wounds were dressed topically according to groups. Rats were sacrificed on days 1, 5, 10, and 15 of treatments.
Wounds were then processed for macroscopic and histological observations. Gelam-honey-dressed
wounds healed earlier (day 13) than untreated and saline treated groups, as did
wounds treated with
Intrasite Gel. Honey-treated
wounds exhibited less scab and only thin
scar formations. Histological features demonstrated positive effects of Gelam honey on the
wounds. This paper showed that Gelam honey dressing on excisional
wound accelerated the process of wound healing.