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Comparison of four ventilatory protocols for computed tomography of the thorax in healthy cats.

AbstractOBJECTIVE:
To identify ventilatory protocols that yielded good image quality for thoracic CT and hemodynamic stability in cats. Animals-7 healthy cats.
PROCEDURES:
Cats were anesthetized and ventilated via 4 randomized protocols (hyperventilation, 20 seconds [protocol 1]; single deep inspiration, positive inspiratory pressure of 15 cm H(2)O [protocol 2]; recruitment maneuver [protocol 3]; and hyperventilation, 20 seconds with a positive end-expiratory pressure of 5 cm H(2)O [protocol 4]). Thoracic CT was performed for each protocol; images were acquired during apnea for protocols 1 and 3 and during positive airway pressure for protocols 2 and 4. Heart rate; systolic, mean, and diastolic arterial blood pressures; blood gas values; end-tidal isoflurane concentration; rectal temperature; and measures of atelectasis, total lung volume (TLV), and lung density were determined before and after each protocol.
RESULTS:
None of the protocols eliminated atelectasis; the number of lung lobes with atelectasis was significantly greater during protocol 1 than during the other protocols. Lung density and TLV differed significantly among protocols, except between protocols 1 and 3. Protocol 2 TLV exceeded reference values. Arterial blood pressure after each protocol was lower than before the protocols. Mean and diastolic arterial blood pressure were higher after protocol 3 and diastolic arterial blood pressure was higher after protocol 4 than after protocol 2.
CONCLUSIONS AND CLINICAL RELEVANCE:
Standardization of ventilatory protocols may minimize effects on thoracic CT images and hemodynamic variables. Although atelectasis was still present, ventilatory protocols 3 and 4 provided the best compromise between image quality and hemodynamic stability.
AuthorsNatalia Henao-Guerrero, Carolina Ricco, Jeryl C Jones, Virginia Buechner-Maxwell, Gregory B Daniel
JournalAmerican journal of veterinary research (Am J Vet Res) Vol. 73 Issue 5 Pg. 646-53 (May 2012) ISSN: 1943-5681 [Electronic] United States
PMID22533395 (Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
Topics
  • Anesthesia (adverse effects)
  • Animals
  • Cats (physiology)
  • Hemodynamics
  • Lung (diagnostic imaging, physiology)
  • Lung Volume Measurements
  • Radiography, Thoracic (methods)
  • Respiration, Artificial (methods)
  • Tomography, X-Ray Computed (methods)

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