Abstract |
The efficacy and safety of a synthetic laminaria tent ( Lamicel; Cabot) in ripening the cervix before induction of labour was compared with prostaglandin E2 ( PGE2) oral tablets used intravaginally. Eighty patients were randomly assigned to use of the laminaria tent (N = 40) or PGE2 (N = 40). There were an equal number of primigravidas and multigravidas in each group. The only significant difference between the groups was the higher frequency of uterine hypertonicity (29 v. 5 : PGE2 v. tent) and consequent fetal distress (5 v. 1 : PGE2 v. tent) in the PGE2 group. However, the duration of labour was shorter in the PGE2 group than in the tent group (10, 14 h v. 11,61 h). These findings indicate that the synthetic laminaria tent is the preferred agent for cervical ripening in high-risk pregnancies and in developing countries.
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Authors | J S Bagratee, J Moodley |
Journal | South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde
(S Afr Med J)
Vol. 78
Issue 12
Pg. 738-41
(Dec 15 1990)
ISSN: 0256-9574 [Print] South Africa |
PMID | 2251632
(Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial)
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Chemical References |
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Topics |
- Administration, Intravaginal
- Adolescent
- Adult
- Cervix Uteri
(physiology)
- Female
- Humans
- Labor, Induced
(methods)
- Laminaria
- Pregnancy
- Prostaglandins E
(administration & dosage)
- Random Allocation
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