Clozapine-induced stuttering: a case report and analysis of similar case reports in the literature.

Abstract

There is limited literature reporting clozapine-associated stuttering. In this case report, we present a case of a young male who developed stuttering with clozapine, which improved with dose reduction. Computer-assisted searches on clozapine-induced stuttering yielded 16 cases, and analysis of these case reports suggests that stuttering may be linked to seizures or movement disorders, but other putative mechanisms may be at work, which need further research.

• Authors: Sandeep Grover, Anant Kumar Verma, Naresh Nebhinani
• Journal: General hospital psychiatry (Gen Hosp Psychiatry) 2012 Nov-Dec Vol. 34 Issue 6 Pg. 703.e1-3 ISSN: 1873-7714 [Electronic] United States
• PMID: 22516217 (Publication Type: Case Reports, Journal Article, Review)
• Copyright: Copyright © 2012 Elsevier Inc. All rights reserved.

Chemical References

• Antipsychotic Agents
• Clozapine

Topics

• Adult
• Antipsychotic Agents (adverse effects)
• Clozapine (adverse effects)
• Dose-Response Relationship, Drug
• Humans
• Male
• Movement Disorders (etiology)
• Schizophrenia (drug therapy)
• Seizures (chemically induced)
• Stuttering (chemically induced)