Abstract | INTRODUCTION: METHODS AND RESULTS: 1096 subjects enrolled in the GIFA study, who had a main discharge diagnosis of ischemic stroke represent the final sample. Drugs considered for the analysis were the following: ACE-inhibitors (ACEI), angiotensin II receptor blockers (ARBs), statins, calcium-channel-blockers (CCBs), antiplatelet (APL) drugs, antivitamin-k (VKAs), and heparins. As outcome indicators we choose in-hospital mortality, cognitive function evaluated by Hodkinson Abbreviated Mental Test (HAMT), and functional status evaluated by activity daily living ( ADL). Indicators of a good outcome were: no in-hospital mortality, HAMT >6 and 0 ADL impaired. Patients with a good outcome showed a higher rate of in-hospital treatment with ACE-inhibitors, calcium-channel blockers and a lower rate of pre-treatment with heparin. CONCLUSIONS:
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Authors | A Tuttolomondo, D Di Raimondo, R Di Sciacca, C Pedone, S La Placa, V Arnao, A Pinto, G Licata |
Journal | Nutrition, metabolism, and cardiovascular diseases : NMCD
(Nutr Metab Cardiovasc Dis)
Vol. 23
Issue 7
Pg. 642-9
(Jul 2013)
ISSN: 1590-3729 [Electronic] Netherlands |
PMID | 22502765
(Publication Type: Journal Article, Multicenter Study)
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Copyright | Copyright © 2012 Elsevier B.V. All rights reserved. |
Chemical References |
- Angiotensin-Converting Enzyme Inhibitors
- Calcium Channel Blockers
- Cardiovascular Agents
- Platelet Aggregation Inhibitors
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Topics |
- Activities of Daily Living
- Aged
- Angiotensin-Converting Enzyme Inhibitors
(therapeutic use)
- Brain Ischemia
(diagnosis, drug therapy, epidemiology, physiopathology)
- Calcium Channel Blockers
(therapeutic use)
- Cardiovascular Agents
(adverse effects, therapeutic use)
- Cognition Disorders
(etiology, prevention & control)
- Comorbidity
- Female
- Geriatric Assessment
- Humans
- Hypercholesterolemia
(epidemiology)
- Hypertension
(epidemiology)
- Italy
(epidemiology)
- Male
- Platelet Aggregation Inhibitors
(therapeutic use)
- Prognosis
- Retrospective Studies
- Stroke
(diagnosis, drug therapy, epidemiology, physiopathology)
- Time Factors
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