HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Clinical utility of biomarkers in premature atherosclerosis.

Abstract
Atherosclerosis is a very complex procedure responsible for the development of coronary artery disease which is the leading cause of death in the civilized world. The obvious pandemic character of atherosclerosis augments the need to discover an ideal biomarker, which will be able to facilitate the clinical diagnosis of the atherosclerosis from the physicians especially in the early stages of the atherosclerotic process. Among the biomarkers that are already used there are classical ones, such as c-reactive protein, interleukins, tumour necrosis factor, apolipoproteins, fibrinogen, homocysteine, and novel promising ones such as lipoprotein-associated phospholipase, asymmetric dimethylarginine, myeloperoxidase, cathepsins and cystatin C. The possibility of combining circulating biomarkers with other methods such as non-invasive and invasive imaging is clinically attractive because this could contribute to the improved diagnosis and understanding of premature atherosclerosis pathogenesis.
AuthorsA-M Kampoli, D Tousoulis, N Papageorgiou, Z Pallatza, G Vogiatzi, A Briasoulis, E Androulakis, C Toutouzas, P Stougianos, C Tentolouris, C Stefanadis
JournalCurrent medicinal chemistry (Curr Med Chem) Vol. 19 Issue 16 Pg. 2521-33 ( 2012) ISSN: 1875-533X [Electronic] United Arab Emirates
PMID22489712 (Publication Type: Journal Article, Review)
Chemical References
  • Biomarkers
Topics
  • Atherosclerosis (diagnosis, metabolism, physiopathology)
  • Biomarkers (metabolism)
  • Diagnostic Imaging
  • Humans

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: