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Efficacy of solifenacin for overactive bladder symptoms, symptom bother, and health-related quality of life in patients by duration of self-reported symptoms: a secondary analysis of the VIBRANT study.

Abstract
In this post-hoc analysis of data from patients with overactive bladder (OAB) in VIBRANT patients receiving solifenacin showed statistically significantly greater improvement versus placebo in most outcome measures regardless of OAB symptom duration (less than five years and five years or longer).
AuthorsKelly Marie Gollar, Douglas G Young, James Bailen, Weizhong He, Sergio Forero-Schwanhaeuser
JournalUrologic nursing (Urol Nurs) 2012 Jan-Feb Vol. 32 Issue 1 Pg. 38-46, 50 ISSN: 1053-816X [Print] United States
PMID22474864 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Muscarinic Antagonists
  • Quinuclidines
  • Tetrahydroisoquinolines
  • Solifenacin Succinate
Topics
  • Adult
  • Female
  • Humans
  • Male
  • Muscarinic Antagonists (therapeutic use)
  • Patient Satisfaction
  • Quality of Life
  • Quinuclidines (therapeutic use)
  • Randomized Controlled Trials as Topic
  • Self Report
  • Solifenacin Succinate
  • Tetrahydroisoquinolines (therapeutic use)
  • Treatment Outcome
  • Urinary Bladder, Overactive (drug therapy, nursing, psychology)

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